PhD students

Dear new GRK1172 members

On behalf of the DFG funded Research Training Group GRK 1172 Biologicals and its steering committee it is our pleasure to welcome you as a new member and to offer thanks for your enthusiasm and interest in the group. We are glad you have decided to join us.

Name	Title of dissertation	Supervisor	Motto
Rasbach, Anke	„Optimization and characterization of cell entry targeted lentiviral vectors”	Prof. Buchholz

Naumann, Anja	"Development of a factor VIII-specific immunotherapy for hemophilia A"	Dr. Königs	Do first of all the necessaries, then all that is possible, and suddenly you manage the impossible. (Franz von Assisi)

Auth, Eileen	"Optimierung einer NK-Zell-Immuntherapie durch Steigerung der NK-Zell-Aktivität gegen Leukämien und Tumore"	Köhl	The way to get started is to quit talking and begin doing. (Walt Disney)

Weber, Christopher	Characterization of the Chikungunya virus entry process and the development of novel antiviral strategies	Schnierle	"Die gefährlichste Weltanschauung ist die Weltanschauung derer, die die Welt nie angeschaut haben." (Alexander von Humboldt)

Our PhD-Team

Name	Title of dissertation	Supervisor	Motto
Abel, Tobias	Selective gene transfer into the endothelial system by lentiviral vectors	Buchholz	Impossible! - So What?!

Abriss, Daniela	Non-viral gene transfer for hemophilia A therapy in the mouse model	Tonn	Failure is simply the opportunity to begin again, this time more intelligently.

Al- Ghaili, Nabil	Role of TCR diversity during genesis of T cell leucemia in mouse models	von Laer	If there is a will, there is a way.

Bajer, Magdalena	Characterisation of active natural compounds as stabilisers of the tumor suppressor Pdcd4.	Brüne/Schmid	"Nearly all the best things that came to me in life have been unexpected, unplanned by me." (Carl Sandburg)

Becker, Yvonne	Inhibition of the oligomerization of AML1/ETO by cell permeable peptides	Grez	"The great tragedy of science is the slaying of a beautiful hypothesis by an ugly fact." (Thomas Henry Huxley)

Brauer, Frances	Design of non-immunogenic peptides for HIV-1 entry inhibition	von Laer	"Science is based on the experience that nature answers intelligent questions intelligently, so if she is silent there may be something wrong with the question." (Albert Szent-Györgyi)

Brehm, Claudia	Adaptive immune therapy using NK cells and inhibitors of histone deacetylase after allogenic stem cell transplantation	Köhl	"Doubt is the father of invention.” (Galileo Galilei)

Doberstein, Kai	Regulation of the L1 cell adhesion molecule in kidney tumor cells	Pfeilschifter	"A scientist is happy, not in resting on his attainments but in the steady acquisition of fresh knowledge." (Max Planck)

Eißmann, Moritz	Identification and analysis of new anti apoptotic proteins expressed in therapy resistant tumors	Zörnig	"If you are out to describe the truth, leave elegance to the tailor." (Albert Einstein)

Fischer, Astrid	Role of 5-Lipoxygenase in proliferation and death of pancreatic cancer cells	Steinhilber	"If we knew what it was we were doing, it would not be called research, would it?" (Albert Einstein)

Jabulowsky, Robert	Recombinant effector molecules of the apoptosis cascade for tumor therapy	Wels	"Thinking is more interesting than knowing, but less interesting than looking." (Johann Wolfgang von Goethe)

Kaufmann, Kerstin	Improved vectors for the gene therapy of X-linked chronic granulomatous disease	Grez	“Imagination is more important than (just) knowledge.” (Albert Einstein)

König, Melanie	Multivariate analysis of age-matched immune reconstitution after allogenic stem cell transplantation from patients with acute leukemia	Köhl	"Discovery consists of seeing what everybody has seen and thinking what nobody has thought." (Albert Szent-Györgyi)

Kraus, Benjamin	Reactivation of human endogenous retrovirus (HERV-K) in cancer and HIV patients: new antigens for vaccination	Schnierle	One of the secrets of life is to make stepping stones out of stumbling blocks.

Kynast, Katharina	Role of microRNA during the development and processing of pain	Niederberger	Das ganze Leben ist ein Quiz - und wir sind nur die Kandidaten.

Langner, Janina	Control of viral replication by engineered riboswitches	Suess	"Our greatest weakness lies in giving up. The most certain way to succeed is always to try just one more time." (Thomas Alva Edison)

Lyssy, Patricia	New strategies for therapies of hemophilia and thrombosis: generation / screening of FIX mutants and transfer to an animal model; screening of FIX inhibitors	Tonn	"The most beautiful thing we can experience is the mysterious. It is the source of all true art and science." (Albert Einstein)

Muik, Alexander	Generating LCMV-GP pseudotyped VSV-based systems for a potential treatment of glioblastoma	von Laer	"All life is problem solving" (Karl Reimund Popper)

Myladoor, Sunitha	Die Rolle des akzessorischen viralen Proteins Vpx bei der Transduktion von ruhenden Zellen mit lentiviralen Vektoren der SIVsmm/SIVmac/HIV2 Gruppe	Schweizer	"Anyone who has never made a mistake has never tried anything new." (Albert Einstein)

Nastase, Madalina Viviana	Effects of adapter molecules on biglycan binding to and signaling via Toll-like receptor	AG Schäfer	"Everything is impossible until it is done” (Robert A. Heinlein)

Neske, Christina	Role of p47phox and possible interaction partners for TLR signaltransduction in dendritic cells	Radeke	"Es kommt nicht darauf an mit dem Kopf durch die Wand zu rennen, sondern mit den Augen die Tür zu finden." (Werner von Siemens)

Oberoi, Pranav	Targeted Induction of tumor-cell death by apoptosis-inducing antibody fusion proteins	Wels	Research is the art of seeing what everyone else has seen, and doing what no-one else has done.

Pahujani, Shweta	Development of a safety-modified retroviral vector for a gene therapy of HIV infection	von Laer	I believe that cosmic religiousness is the strongest and most noble driving force of scientific research.

Qi, Zhou	Selektiver Gentransfer in CD8-positive T-Zellen	Buchholz

Roth, Stefanie	Optimization of recombinant Factor VIII production in heterologous cell systems and analysis of its secretion pathway Poster Prize September 2008 at the DGTI, honoured for excellente sientific work	Tonn	Unexpected results are often the better ones in research!

Rudloff, Ina	Regulation, function and therapeutic potential of IL-22 in inflammation	Mühl	"The future belongs to those who believe in the beauty of their dreams" (Eleanor Roosevelt)

Russe, Quintus	Untersuchungen zur Rolle von NF-kappaB- modulierenden Kinasen bei entzündlichen Schmerzen	Niederberger	Non quia difficilia sunt non audemus, sed quia non audemus difficilia sunt

Scheiermann, Patrick	Das therapeutische Potential von Interleukin-22 bei systemischer Entzündung	Mühl

Schmithals, Christian	Improvement of drug delivery in a transgenic HCC mouse model	Piiper	"There is nothing wrong with challenging conventional wisdom -- continuing challenge is a core feature of science……" (Wesley R. Elsberry)

Schröder, Matthias	Endogenous sphingolipids, analoga and their metabolism in dendritic cells	Radeke	Wenn die Klügeren immer nachgeben, geschieht nur das, was die Dummen wollen.

Sokocevic, Alma	Synthesis and characterisation of Parvulustat and its derivatives	Engels	Don´t say always what you know, but always know what you say.

Steinmeyer, Nico	Regulation and function of neuronal Hu-like mRNA-binding proteins in cancer and disease	Eberhardt	"In der Wissenschaft gleichen wir alle nur den Kindern, die am Rande des Wissens hier und da einen Kiesel aufheben, während sich der weite Ozean des Unbekannten vor unseren Augen erstreckt." (Isaac Newton)

Volk, Andreas	Development of AAV-derived vectors for antiviral HIV gene therapy	von Laer	"The important thing is not to stop questioning." (Albert Einstein)

Zhou, Mingkui	The role of neutralizing antibodies in HIV-1 infected elite controllers	Dietrich	In doing we learn.